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The Specific Features of Regeneration Processes of the Blood in Remote Periods Following Injury of the Organism with Sr90 and X-Rays (in Russian)

Journal Article · · Meditsinskaya Radiologiya (Russian Federation)
OSTI ID:4161560
Published data indicate a partial or complete normalization period in hematopoiesis of animals exposed to chronic radiation injuries induced by 5 to 15 r of x radiation or by injections of Sr90. However, in some cases acute sickness appears during the restoration period. Studies were made of 41 dogs; 17 dogs were exposed to x radiation and 24 dogs were given Sr90 injections. Ten of the 17 exposed to x radiation received 10 r daily and the other seven received 5 r daily. Of the 10 receiving 10 r, three dogs did not exhibit any normalization period. The remaining seven receiving 10 r and the seven receiving 5 r exhibited a definite restoration of the hematopoietic function after 35 to 50 weeks (total doses of 2000 and 1200 r, for the respective groups). Single intravenous injections of 0.1 to 0.2 mc/kg of Sr90 resulted in acute radiation sickness with 20% fatality after 1 to 2 months. In the remaining 80%, peripheral blood erythrocytes were restored to the initial number 5 months following the injection. Twenty to thirty-five months later, the erythrocyte number exceeded the initial number by 30 to 40%.
Sponsoring Organization:
USDOE National Nuclear Security Administration (NNSA), Nuclear Criticality Safety Program (NCSP); US Atomic Energy Commission (AEC)
DOE Contract Number:
NONE;
NSA Number:
NSA-15-001315
OSTI ID:
4161560
Journal Information:
Meditsinskaya Radiologiya (Russian Federation), Journal Name: Meditsinskaya Radiologiya (Russian Federation) Journal Issue: 8 Vol. 5; ISSN 0025-8334
Country of Publication:
Russian Federation
Language:
Russian

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