CHEMICAL PROTECTION OF THE ALIMENTARY TRACT OF WHOLE-BODY X-IRRADIATED MICE. 1. CHANGES IN WEIGHT, HISTOLOGY, AND CELL DIVISION IN RELATION TO NUCLEIC ACID AND PROTEIN SYNTHESIS

Journal Article · Fri Jul 01 04:00:00 EDT 1960 · Intern. J. Radiation Biol.

OSTI ID:4147109

Maisin, J R; Novelli, G D; Doherty, D G; Congdon, C C

Chemical protection afforded by AET to the alimentary tracts of mice against radiation doses of 900, 1500, and 2000 r was studied. Although the small intestine was studied most intensively, data were also collected on the esophagus, stomach, caecum and colon. For all measurements AET-treated mice were compared with nontreated mice and normal controls. The weights of organs and their contents were measured separately. Histological evaluation was made throughout the radiation injury and recovery period. Mitotic counts were obtained on the histologic sections of the alimentary tracts. Chemical analyses, including DNA-, RNA-, and protein-synthesis were performed on the small intestine at the 1500-r exposure level only. All measurements demonstrated a marked protective action of AET on the alimentary tract at these radiation exposure doses. (auth)

• Research Organization: Oak Ridge National Lab., Tenn.
• NSA Number: NSA-14-025328
• OSTI ID: 4147109
• Journal Information: Intern. J. Radiation Biol., Journal Name: Intern. J. Radiation Biol. Vol. Vol: 2
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

AET
BIOCHEMISTRY
BIOLOGY AND MEDICINE
CHEMICALS
DNA
INTESTINE
MICE
MICROSCOPY
MITOSIS
NUCLEIC ACIDS
ORGANIC SULFUR COMPOUNDS
PROTEINS
QUALITATIVE ANALYSIS
QUANTITY RATIO
RADIATION DOSES
RADIATION INJURIES
RADIATION PROTECTION
RECOVERY
RIBONUCLEIC ACID
STOMACH