A PILOT EXPERIMENT WITH MICE, USING HALDANE'S METHOD FOR DETECTING INDUCED AUTOSOMAL RECESSIVE LETHAL GENES
Journal Article
·
· Journal of Genetics (U.S.)
A search was made for x-ray-induced recessive autosomal lethal genes in the mouse, using a method proposed by J. B. S. Haldane, the experiment was intended primarily to test the method. It was found that the method is less efficient for measuring mutation rates than the specificlocus method. Data obtained enabled a lower limit to be set for the x-ray dose required to induce one recessive autosomal lethal in spermatogonia, namely 810 r. No upper limit could be set. Relevance to human problems is discussed. (auth)
- Research Organization:
- Medical Research Council's Radiobiological Research Unit, Harwell, Berks, Eng.
- Sponsoring Organization:
- USDOE
- NSA Number:
- NSA-14-012472
- OSTI ID:
- 4146018
- Journal Information:
- Journal of Genetics (U.S.), Journal Name: Journal of Genetics (U.S.) Vol. Vol: 56; ISSN JOGNA
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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