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MODIFICATION BY IONIZING RADIATION OF THE CENTRAL NERVOUS REACTIVITY TO STIMULATING DRUGS

Journal Article · · Activitas Nervosa Super.
OSTI ID:4145995
A study was made of the effect of drugs stimulating the CNS in mice, rats, and rabbits during 6 days after irradiation with a mean lethal dose of x rays. It was found that mice showed a lowered intravenous toxicity and increased convulsion to a lethal dose of pentazol, pentazol treated rats had a lowered motor activity after an original hyperactivity, and rabbits showed shortening of the pentazol ECoG changes. Some rats developed a defensive conditioned reflex under standard conditions. These were improved by caffein, methylphenyldat, and benzedrine. It was concluded that radiation probably does not affect definite processes in a special way, but probably disturbs energetic metabolism. (OTS)
Research Organization:
Charles Univ., Prague
NSA Number:
NSA-18-005014
OSTI ID:
4145995
Journal Information:
Activitas Nervosa Super., Journal Name: Activitas Nervosa Super. Vol. Vol: 5
Country of Publication:
Country unknown/Code not available
Language:
English

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