Distribution of Se⁷⁵ in Serum Proteins of Chicks and Influence of Selenium on Albumin Recovery.

Journal Article · Fri Nov 01 04:00:00 EST 1963 · Experimental Biology and Medicine

DOI:https://doi.org/10.3181/00379727-114-28723· OSTI ID:4144817

Walter, E. D.; Jensen, L. S.; Dunlap, J. S.

Se⁷⁵ was orally administered to 3-week-old chicks fed either selenium deficient or supplemented diets. Distribution of Se⁷⁵ in serum proteins with time and its effect on serum protein pattern were determined electrophoretically. Selenium in the diet had no effect on the distribution of Se⁷⁵ in the protein fraction, but markedly decreased its retention. After two hours the major portion of the dose was found in the beta and gamma fraction and the activity in this fraction increased with time. Marked increases in albumin/ globulin (A/G) ratios in depleted chicks were observed within 96 hours after administration of Se⁷⁵. Albumin was increased and globulin fractions were decreased. Increases in A/G ratios, somewhat smaller in magnitude, were also noted in chicks receiving a diet supplemented with selenium. (auth)

• Research Organization: Washington State Univ., Pullman
• Sponsoring Organization: USDOE
• NSA Number: NSA-18-003470
• OSTI ID: 4144817
• Journal Information: Experimental Biology and Medicine, Journal Name: Experimental Biology and Medicine Journal Issue: 2 Vol. 114; ISSN 1535-3702
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

AGE
ALBUMINS
BIOLOGY AND MEDICINE
BIRDS
BLOOD SERUM
CHICKENS
DIET
DISTRIBUTION
ELECTROPHORESIS
GLOBULINS
PROTEINS
VARIATIONS