INFLUENCE OF DIETARY VITAMIN E AND SELENIUM ON DISTRIBUTION OF Se$sup 75$ IN THE CHICK

Journal Article · Mon Apr 01 04:00:00 EST 1963 · Proc. Soc. Exptl. Biol. Med.

DOI:https://doi.org/10.3181/00379727-112-28203· OSTI ID:4712735

Jensen, L S; Walter, E D; Dunlap, J S

S>Three-week-old chicks fed either a vitamin-E--deficient or supplemented diet were intraperitoneally injected with Se/sup 75/, and distribution of the isotope was determined in various tissues at 24, 48, and 168 hours after injection. Similarly, 2-week-old chicks fed a selenium deficient or supplemented diet were given an oral dose of Se/sup 75/ and the distribution of the isotope in several tissues was determined at 24 and 168 hours after administration. Vitamin E had no effect on distribution of selenium, but selenium itself had a marked effect on the uptake and retention of radioselenium. One-half of the dose was retained by selenium-deficient chicks at 7 days, whereas only 1/5 of the dose was retained by chicks fed 1 ppm selenium from day-of-age. Considerable selenium was deposited and retained in the cerebellum of chicks even though this element cannot prevent encephalomalacia. (auth)

• Research Organization: Washington State Univ., Pullman
• Sponsoring Organization: USDOE
• NSA Number: NSA-17-023064
• OSTI ID: 4712735
• Journal Information: Proc. Soc. Exptl. Biol. Med., Journal Name: Proc. Soc. Exptl. Biol. Med. Vol. Vol: 112
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

AGE
BIOLOGY AND MEDICINE
BIRDS
BRAIN
CEREBELLUM
CHICKENS
DIET
DISEASES
FOOD
ISOTOPES
METABOLISM
QUANTITATIVE ANALYSIS
QUANTITY RATIO
SELENIUM
SELENIUM 75
TISSUES
VITAMIN E
VITAMINS