INFLUENCE OF DIETARY VITAMIN E AND SELENIUM ON DISTRIBUTION OF Se$sup 75$ IN THE CHICK
S>Three-week-old chicks fed either a vitamin-E--deficient or supplemented diet were intraperitoneally injected with Se/sup 75/, and distribution of the isotope was determined in various tissues at 24, 48, and 168 hours after injection. Similarly, 2-week-old chicks fed a selenium deficient or supplemented diet were given an oral dose of Se/sup 75/ and the distribution of the isotope in several tissues was determined at 24 and 168 hours after administration. Vitamin E had no effect on distribution of selenium, but selenium itself had a marked effect on the uptake and retention of radioselenium. One-half of the dose was retained by selenium-deficient chicks at 7 days, whereas only 1/5 of the dose was retained by chicks fed 1 ppm selenium from day-of-age. Considerable selenium was deposited and retained in the cerebellum of chicks even though this element cannot prevent encephalomalacia. (auth)
- Research Organization:
- Washington State Univ., Pullman
- Sponsoring Organization:
- USDOE
- NSA Number:
- NSA-17-023064
- OSTI ID:
- 4712735
- Journal Information:
- Proc. Soc. Exptl. Biol. Med., Vol. Vol: 112; Other Information: Orig. Receipt Date: 31-DEC-63
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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