THE SYNTHESIS OF CHYLOMICRA AND MAINTENANCE OF NORMAL BLOOD SUGAR LEVELS BY ISOLATED, PERFUSED RAT LIVER
Technical Report
·
OSTI ID:4144026
Isolated rat livers were perfused for 4.5 hr with wholeblood taken from fed rats. The perfusate, bile, and livers were analyzed for changes in lipids and carbohydrates. In addition, the fate of the C/sup 14/ label of injected palmitic acid1-C/sup 14/-labeled chylomicrons was determined. It was shown that the isolated-perfused liver, taken from a fed rat, can synthesize and release chylomicra into the blood. The isolated-perfused liver is able to establish and maintain the blood sugar and lactic acid levels at normal values. The nutritional status of the liver was a determinant factor in the synthesis and utilization of lipids by this organ. (auth)
- Research Organization:
- Naval Radiological Defense Lab., San Francisco
- NSA Number:
- NSA-14-025151
- OSTI ID:
- 4144026
- Report Number(s):
- USNRDL-TR-426
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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