DYE-SENSITIZED PHOTO-REACTIVATION OF X-RAY DAMAGE IN DIPLOID YEAST
Experimental cells of diploid yeast were suspended in a phosphate buffer at pH 7. This suspension was exposed first to x rays sufficient to inactivate a predetermined fraction of the population. Purified acridine orange was then added. After 20 min the cells were irradiated with visible light. In all cases, this subsequent irradiation with low doses of visible light increased the surviving fraction, indicating a repair or by-pass of part of the damage produced by the x rays. With increasing dose, simultaneous killing by the visible light first lessened and finally overcame the observed reactivations. This reactivation was not found in haploid yeast. (M.C.G.)
- Research Organization:
- Univ. of Chicago
- Sponsoring Organization:
- USDOE
- NSA Number:
- NSA-14-025336
- OSTI ID:
- 4142893
- Journal Information:
- Nature, Journal Name: Nature Vol. Vol: 187
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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