TREATMENT OF VIRUSES
Patent
·
OSTI ID:4142521
A vaccine preparation method was developed for destroying the infectivity of live viruses while retaining the antigenicity. The method comprises exposing the virus to 0.5 to 6 x 10/sup 6/ rad of ionizing radiation (preferably gamma) in the presence of a protective agent. The protective agent is antioxidant in nature and should be used in amounts from 0.05to 0.3% (wt/vol). Histidine and sodium p-aminohippurate are preferred for influenza and mumps viruses respectively. The protective effects of various chemicals on the antigenicity of irradiated influenza A virus are illustrated. (D.L.C.)
- Research Organization:
- Originating Research Org. not identified
- NSA Number:
- NSA-18-003583
- OSTI ID:
- 4142521
- Report Number(s):
- CA 660388
- Resource Relation:
- Patent File Date: 1961 Jun 13; Other Information: Orig. Receipt Date: 31-DEC-64
- Country of Publication:
- Canada
- Language:
- English
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