Effect of Pre-Immunized Rat Bone Marrow on Lethally Irradiated Mice
Journal Article
·
· Experimental Biology and Medicine
A comparison was made of time and incidence of death between lethally irradiated mice injected with non-immune rat bone marrow and those injected with marrow from rats pre-immunized against recipient strain of mice. Statistical analysis of data showed no significant differences between the 2 groups of animals. Similarly, a lack of significant difference was observed with marrow- treated mice given a supplementary injection of moderate amounts of either nonimmune or pre-immunized rat spleen cells. The failure of sufficient numbers of immunologically active cells to colonize and proliferate is discussed as the most probable interpretation of the results.
- Research Organization:
- U.S. Naval Radiological Defense Lab., San Francisco
- Sponsoring Organization:
- USDOE
- NSA Number:
- NSA-14-018786
- OSTI ID:
- 4141782
- Journal Information:
- Experimental Biology and Medicine, Journal Name: Experimental Biology and Medicine Journal Issue: 3 Vol. 104; ISSN 1535-3702
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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