RADIATION-INDUCED ACUTE SEBORRHEIC MANIFESTATIONS AFTER RADIOTHERAPY FOR BASOCELLULAR EPITHELIOMA. CURE WITH ANTIBIOTICS (in French)
An unusual case of radiodermatitis in a 58-yr-old woman operated on for basocellular epithelioma of the inner aspect of the right eyelid is described. Postoperative radiation treatment was given as follows: 2000-r doses of unfiltered 50-kv x rays, three times, one week apart, for a total of 6000 r. After 15 days, slight ulceration of the irradiated portion and marked dermatitis of the surrounding skin area were noted. Local application of solution and ointments provided analgesia but did not cure the condition, which spread from the cheek to nose and chin, and was accompanied by seborrhea, over a period of 16 months. Bacterial examination revealed staphylococci, which promptly responded to antibiotic (erythromycin) treatment. A similarity was noted between this patient's condition and the more common reactions of children to scalp radiation treatment for ringworm. Other cases are cited to show occasional unusual side- effects of radiation treatment, and the possibility that the present case represents a unique type of skin response to radiation is discussed. Allergy alone, it is contended, probably does not explain the reaction observed, but a bacterial infection was involved in the reaction. It is concluded that this case and the two others mentioned indicate that other factors are of importance, the nature of which needs to be determined by further study. (BBB)
- Research Organization:
- Originating Research Org. not identified
- NSA Number:
- NSA-18-003518
- OSTI ID:
- 4128419
- Journal Information:
- Bull. Soc. Franc. Dermatol. Syphilig., Journal Name: Bull. Soc. Franc. Dermatol. Syphilig. Vol. Vol: 68
- Country of Publication:
- Country unknown/Code not available
- Language:
- French
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