THE DETERMINATION OF HYALURONIDASE, HISTAMINE AND ALBUMIN FRACTIONS IN PEOPLE SUBJECTED TO CONTINUOUS RADIATION EXPOSURE (in Russian)
Journal Article
·
· Trudy Vsesoyuz. Konf. Med. Radiol.
OSTI ID:4126196
Hyaluronidase which promotes the breakdown of hyaluronic acid in protective polysaccharide barriers may be associated with the increased permeability of tissue during radiation sickness. The average hyaluronldase content in the blood serum of healthy people was 0 to 2 units as determined by the prolongation of the coagulation time of mucin or by a decrease in viscosity of the albumin addition compound with hyaluronic acid. A group of 123 people subjected to ionizing radiation were divided into three sub-groups less than 1 year, 1 to 3 years, and more than 3 years length of service). The greatest number of people (about 40%) showed an increased hyaluronldase content (3.3 to 10 units) at 1 to 3 years service. Working with chemically toxic materials results in a 40% incidence of heightened hyaluronidase content (3.3 to 10 units). An increased histamine content varying from 1l to 25 gamma % was found in the blood plasma of people subjected to ionizing radiation. The albumin fraction from blood plasma showed a decrease in albumin (41.5 to 54.6% compared to a normal value of 58%), an increase in gamma -globulin (18 to 25.6% compared to a normal value of 17.2%), and an increase in beta -globulin (l4 to 19.8% compared to a normal value of 13.l%). People with 1 to 3 years of service also showed an increase in alpha /sub 2/-globulin (9.9 to 14.8% compared to a normal value of 7.6%). The changes in globulin content were accompanied by changes in hyaluronidase content which increase the permeability of tissues. (TTT)
- Research Organization:
- Originating Research Org. not identified
- NSA Number:
- NSA-15-002509
- OSTI ID:
- 4126196
- Journal Information:
- Trudy Vsesoyuz. Konf. Med. Radiol., Journal Name: Trudy Vsesoyuz. Konf. Med. Radiol.
- Country of Publication:
- Country unknown/Code not available
- Language:
- Russian
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