Fractional radon retention in bone

Journal Article · Sat Nov 01 04:00:00 EST 1975 · Health Phys., v. 29, no. 5, pp. 761-765

DOI:https://doi.org/10.1097/00004032-197511000-00017· OSTI ID:4124446

Mays, C W; Lloyd, R D; Van Dilla, M A

Radon-to-radium ratios have been measured in defleshed, canned, and frozen bones of 50 beagles dying 5 to 2988 days after the intravenous injection of $sup 226$Ra. The expression Rn/Ra = (0.075 +- 0.010)t/sup 0.158 +- 0.004/ (1 - e/sup -0.181 t/) at t days describes the dependence of the Rn/Ra ratio in these bones upon time after administration, and was shown to be independent of age at injection or relative injected activity. This equation also appears valid for dogs that received their radium in six equal injections spaced over a period of 280 days, when t is considered as time after midinjection, at least when the time after mid-injection exceeds the duration of injections. Comparison of results for dogs with those reported for mice, rats, chinchillas, and humans showed that about 68 percent of the individual values for these other species were within +- S. D. of the equation for beagles. This suggests that skeletal Rn/Ra ratios as a function of time may be somewhat species independent. Therefore, these ratios depend almost exclusively upon the time following radium deposition. (auth)

• Research Organization: Univ. of Utah, Salt Lake City
• NSA Number: NSA-33-009635
• OSTI ID: 4124446
• Journal Information: Health Phys., v. 29, no. 5, pp. 761-765, Journal Name: Health Phys., v. 29, no. 5, pp. 761-765; ISSN HLTPA
• Country of Publication: United Kingdom
• Language: English

Related Subjects

*RADON-- RETENTION
*SKELETON-- RADIONUCLIDE KINETICS
560172* --Biomedical Sciences
Applied Studies--Radiation Effects--Nuclide Kinetics & Toxicology--Animals
BEAGLES
COMPARATIVE EVALUATIONS
INJECTION
MAN
MATHEMATICAL MODELS
MICE
N48720* --Life Sciences--Nuclide Kinetics & Toxicology-- Animals
RADIUM
RADON 226
RATS
TIME DEPENDENCE