Comparative study of /sup 99m/Tc-polyphosphate and /sup 99m/Tc- diphosphonate

Journal Article · Sun Jun 01 04:00:00 EDT 1975 · Nucl.-Med., v. 14, no. 2, pp. 83-90

OSTI ID:4124306

Henne, W; Pixberg, H U; Pfannenstiel, P

sup(99m)Tc-labelled phosphates are the bone seeking agents of choice. The comparison of sup(99m)Tc-polyphosphate (Poly-P) and sup(99m)Tc-ethane-1- hydroxy-1,1-diphosphonate (EHDP) shows a better in vitro stability of the latter during the first two hours after preparation. The blood clearance of EHDP is superior to Poly-P resulting in reduced background activity at scanning time. Renal excretion over a 4-hour period of urine sampling showed no significant differences between both substances. Blood activity is independent of diuresis. (orig.)

• Research Organization: Deutsche Klinik fuer Diagnostik, Wiesbaden (F.R. Germany). Sektion Nuklearmedizin
• NSA Number: NSA-33-009672
• OSTI ID: 4124306
• Journal Information: Nucl.-Med., v. 14, no. 2, pp. 83-90, Journal Name: Nucl.-Med., v. 14, no. 2, pp. 83-90; ISSN NMIMA
• Country of Publication: Germany
• Language: German

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