THE EFFECT OF GAMMA RADIATION WITH Co$sup 60$ ON THE EXPLANTED CONNECTIVE TISSUE OF THE CHICKEN EMBRYO

Journal Article · Thu Jul 21 04:00:00 EDT 1960 · Doklady Akad. Nauk S.S.S.R.

OSTI ID:4116197

Ivanitskaya, A F; Faleeva, Z N

Connective tissue from the heart of 7- to 8-day-old chicken embryos was cultured in chicken plasma or embryo extract, and irradiated with a dose of 100 to 200,000 r 24 hr after explantation. The growth, per cent of mitoses and certain cytological characteristics were used to follow the reactions in the tissue cells. It was found that small doses (100 rl showed neither a harmful nor stimulating eifect. Doses of 1000 to 5000 r lead to the appearance of pathological forms and a reduction in ihe number of mitoses immediately after irradiation. However, normal mitotic activity was resumed in the last days of the life of the culture and indicated that reparative processes were going on in the tissue. Doses of 50,000 to 75.000 r cause a complete cessation of mitotic activity in the cell, and the accumulation of large amounts of detritus, but the growth zone continued to increase. Doses of 100,000 to 200,000 r cause degenerative changes in the cells, and a continuous decrease in the number of cells. (TTT)

• Research Organization: Severtsov Inst. of Animal Morphology, Academy of Sciences, USSR
• NSA Number: NSA-15-007209
• OSTI ID: 4116197
• Journal Information: Doklady Akad. Nauk S.S.S.R., Journal Name: Doklady Akad. Nauk S.S.S.R. Vol. Vol: 133
• Country of Publication: Country unknown/Code not available
• Language: Russian

Related Subjects

ANIMAL CELLS
BIOLOGY AND MEDICINE
BLOOD PLASMA
COBALT 60
CYTOLOGY
EMBRYOS
GAMMA RADIATION
HEART
MITOSIS
RADIATION DOSES
RADIATION EFFECTS
TISSUES