THE EFFECT OF IONIZING IRRADIATION ON THE LIPID COMPOSITION OF THE LIVER MITOCHONDRIA OF RATS
Journal Article
·
· Archives of Biochemistry and Biophysics (U.S.)
ABS>The lipids of freeze-dried liver mitochondria of nonirradiated and x- ray irradiated rats were examined by chemical analysis, paper chromatography, infrared spectroscopy, and gas-liquid chromatography. A polyglycerolphosphatide fraction of great similarity with bis(phos phatidic) acid was isolated and tentatively characterized. Fatty acid analysis suggests that this fraction is not composed of a single lipid but of a group of lipids of different fatty-acid composition. Ionizing irradiation of the animals causes a significant increase of the mitochondrial polyglycerolphosphatides. As the other fractions were not similarly affected by the irradiation, polyglycerolphosphatide became one of the major lipid fractions of the liver mitochondria of irradiated rats. (auth)
- Research Organization:
- Philadelphia General Hospital
- Sponsoring Organization:
- USDOE
- NSA Number:
- NSA-15-008534
- OSTI ID:
- 4110117
- Journal Information:
- Archives of Biochemistry and Biophysics (U.S.), Journal Name: Archives of Biochemistry and Biophysics (U.S.) Vol. Vol: 92; ISSN ABBIA
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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