RADIOIODINE STUDIES OF FETAL AND OTHER THYROIDS. Technical Progress Report
Preliminary results are presented from studies on the uptake of I/sup 131/ by human fetal thyroid glands after radioiodine had been given to the mother. Results are summarized on a total of 26 fetal thyroids. Data show that iodine uptake can be demonstrated as early as the twelfth week. The histologic appearance of the thyroid glands is correlated with accumulation of iodine. Radioautograms were prepared of each fetal thyroid. Data are included on levels of bound iodine in blood plasma during pregnancy. It is concluded that the period of fetal development from 21 to 23 weeks may be critical for radioiodine- induced damage. The possibility of genetic damage from the ad ministration of I/ sup 131/ during pregnancy is discussed. Measurements were made of I/sup 131/ accumulation in ovarian tissue at different times after administration. In some cases the ovarian studies were combined with fetal thyroid studies. (C.H.)
- Research Organization:
- Iowa. State Univ., Iowa City
- NSA Number:
- NSA-15-008434
- OSTI ID:
- 4107240
- Report Number(s):
- TID-11645
- Country of Publication:
- United States
- Language:
- English
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RADIOIODINE STUDIES OF FETAL AND OTHER THYROIDS. Technical Progress Report, January 1962