THE EFFECT OF VITAMIN B$sub 1$ AND PP ON THE METABOLISM OF CHOLESTEROL AFTER IRRADIATION

Journal Article · Sun Jan 01 04:00:00 EST 1961 · Visn. Kiivs'k. Univ., Ser. Biol.

OSTI ID:4092699

Sopin, E F

A study was made of cholesterol metabolism in the liver, muscles, brain, and blood. The experiments were conducted with the assistance of C/sup 14/H/sub 3/OOH, which was introduced into gainea pigs two hours previous to the acute testing in the amount of 50,000 imp/min to each g of live animal weight. On the basis of the results it was established that the content of cholesterol following irradiation, compared with the normal, is increased in the liver and blood, decreased in the brain, and practically unchanged in the muscles. The intensity of renovation of cholesterol after irradiation decreases in the liver, muscles, and brain. When Vitamin B/sub 1/ and PP is given the irradiated animal, the content of cholesterol increases in all of the organs studied, except in the blood where it diminishes. The intensity of the renovation of cholesterol in the irradiated animal given Vitamin B/sub 1/ and PP remains lowered in the liver and muscles, compared with the normal, and it noticeably increases in the brain, approximating the normal. (Referativnyy Zhurnal, Biologicheskaya Khimiya, No. 18, Sept. 1963)

• Research Organization: Originating Research Org. not identified
• NSA Number: NSA-18-009928
• OSTI ID: 4092699
• Journal Information: Visn. Kiivs'k. Univ., Ser. Biol., Journal Name: Visn. Kiivs'k. Univ., Ser. Biol. Vol. Vol: No. 4
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

BIOLOGY AND MEDICINE
BLOOD
BRAIN
CARBON 14
CHOLESTEROL
GUINEA PIGS
IRRADIATION
LABELLED COMPOUNDS
LIVER
METABOLISM
MUSCLES
ORGANIC ACIDS
RADIATION DOSES
RADIATION PROTECTION
VARIATIONS
VITAMIN B-1
VITAMIN PP
VITAMINS