EFFECTS OF RADIATION ON NUCLEIC ACID METABOLISM IN MICE. I. STUDIES ON RADIOSENSITIVITY OF VARIOUS ORGANS
Journal Article
·
· Nippon Igaku Hoshasen Gakkai Zasshi (Japan)
OSTI ID:4090671
The weight and nucleic acid content of the thymus, spleen, liver, and testis in mice were measured after x irradiation. As for nucleic acid metabolism, the thymus, spleen, and testis were highly radiosensitive. On the contrary, the liver was relatively radioresistant. Nucleic acid metabolism after irradiation was divided into 2 phases: in the first the synthesis of nucleic acid was depressed markedly, and in the second recovery from the depression occurred. With whole-body irradiation by supralethal dose the second phase was absent, and ongan weight as well as nucleic acid content decreased gradually, and no recovery occurred. Even when the thymus and testis were shielded from x rays, indirect effects from the remaining portion of the body were observed. The nucleic acid metabolism in the thymus, spleen, and testis was disturbed by exposure to sublethal doses of 200 to 300 r. (auth)
- Research Organization:
- Kyoto Univ.
- NSA Number:
- NSA-15-020605
- OSTI ID:
- 4090671
- Journal Information:
- Nippon Igaku Hoshasen Gakkai Zasshi (Japan), Journal Name: Nippon Igaku Hoshasen Gakkai Zasshi (Japan) Vol. Vol: 19; ISSN NHGZA
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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