COMPARATIVE METABOLISM OF BARIUM-133 AND CALCIUM-45 BY EMBRYONIC BONE GROWN IN VITRO
The comparative metabolism of /sup 133/Ba and /sup 45/Ca by embryonic chick bone grown in vitro is reported. The uptake of /sup 133/Ba was influenced by the period of incubation in the labeled medium, size of bones, and concentrations of Ca and Ba ions in the medium. Culturing of embryonic bone in vitro showed that chick and rat bone could discriminate against /sup 133/Ba in favor of /sup 45/Ca. Treating the bones with formalin destroyed their ability to discriminate against /sup 133/Ba. In live bones, the selective mechanism functioned at 37 deg C but not at 3 deg C. The results suggested that discrimination against Ba in favor of Ca was largely a function of viable bone cells. (auth)
- Research Organization:
- Public Health Service, Montgomery, Ala.
- Sponsoring Organization:
- USDOE
- NSA Number:
- NSA-18-015803
- OSTI ID:
- 4078903
- Journal Information:
- Radiation Res., Journal Name: Radiation Res. Vol. Vol: 21
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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