HISTOCHEMICAL INVESTIGATIONS OF GLYCOGEN IN EYEBALL TISSUE IN RADIATION SICKNESS
Dogs and rabbits were irradiated with x-ray doses of 692 and 792 r, respectively. The animals were sacrificed at different periods following irradiation and the enucleated eyeballs embedded in celloidin and paraffin for histochemical study. Glycogen was nonuniformaly distributed as granules, lumps, powder, or a homogeneous mass in the normal coats of the eye. A high glycogen content was found in the eye muscles, conjunctival epithelium, sustentacular fibers of Muller, and vessels, especially those of the iris. There was a medium amount of glycogen in the corneal epithelium, rod and cone layer, ciliary muscles, and muscle bundles of the iris. Little glycogen was found in the outer plexiform and inner nuclear layers of the retina and in the substantia propria. Glycogen was lacking in the endothelium of Descemet's membrane and of the iris, the epithelium of the crystalline lens, and the glial cells of the optic nerve. The content and distribution of glycogen changed, depending on the severity and stage of radiation sickness. Increased glycogen content was noted in the eye muscles, outer layers of the retina, and vitreous body. A decrease was noted in the inner layers of the retina, the conjunctival epithelium, and in the nuclei of the crystalline lens. Glycogen disappeared in the crystalline lens in the areas of homogenation and fibrogenesis. (auth)
- Research Organization:
- Inst. of Roentgenology and Radiology, Azerbaijanian SSR
- NSA Number:
- NSA-18-015837
- OSTI ID:
- 4078378
- Journal Information:
- Federation Proc., Transl. Suppl., Vol. Vol: 23: Pt. II; Other Information: Orig. Receipt Date: 31-DEC-64; Related Information: Translated from Arkh. Patol., 25: No. 3, p.56, 1963
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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