ELECTROSHOCK SEIZURES IN RAT AFTER X-IRRADIATION

Journal Article · Tue Jan 01 04:00:00 EST 1963 · Sb. Ved. Praci Lekar. Fak. Karlovy Univ. Hradei Kralove

OSTI ID:4071230

Farsky, J; Komenda, S; Pospisil, E; Schober, B; Spitalsky, J

Studies were made on the effects of x radiation on the central nervous system of rats using electroshock seizures as indicators. Whole-body irradiation with doses ranging from 390 to 700 r (in air) shortened the duration of tonic seizures 3 hr after irradiation for at least 3 days. Cysteine in a dose of 800 mg/kg, administered 10 min before irradiation was followed by a statistically significant increase of the duration of tonic seizures whereas in non-irradiated rats it was without effect. It was concluded that electroshock seizures indicate direct damage to the CNS. (P.C.H.)

• Research Organization: Originating Research Org. not identified
• NSA Number: NSA-18-009885
• OSTI ID: 4071230
• Journal Information: Sb. Ved. Praci Lekar. Fak. Karlovy Univ. Hradei Kralove, Journal Name: Sb. Ved. Praci Lekar. Fak. Karlovy Univ. Hradei Kralove Vol. Vol: 6
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

BIOLOGY AND MEDICINE
BODY
CYSTEINE
ELECTROSHOCK
MEASURED VALUES
MEDICINE
NERVOUS SYSTEM
QUANTITY RATIO
RADIATION DOSES
RADIATION EFFECTS
RADIATION INJURIES
RADIATION PROTECTION
RATS
X RADIATION