HUMORAL FACTORS IN CNS CHANGES IN EXPERIMENTAL RADIATION SICKNESS

Journal Article · Sun Mar 01 04:00:00 EST 1964 · Federation Proc., Transl. Suppl.

OSTI ID:4070231

Gorizontov, P D; Shcherbova, E N

Irradiation of single rats with a dose of 1100 r gives rise to Central Nervous System (CNS) changes in the form of the phases of increased and reduced cortical activity and alterations of the reactivity and excitability threshold of the cortex. Unexpectedly, however, the changes are much greater in a parabiotic partner subjected to irradiation of the same order than in intact animals. Exposure of single rats to 25 r has a very mild effect on the cerebral activity. In a parabiont under identical conditions the same dose produces marked electroencephalographic (EEG) changes that are to a certain extent similar to changes produced by the dose of 1100 r in the unprotected partner. Results indicate that changes in the humoral medium of the body have an important effect on the development of radiation induced CNS reactions. (auth)

• Research Organization: Originating Research Org. not identified
• NSA Number: NSA-18-015836
• OSTI ID: 4070231
• Journal Information: Federation Proc., Transl. Suppl., Journal Name: Federation Proc., Transl. Suppl. Vol. Vol: Pt. II, 23
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

BIOLOGY AND MEDICINE
BRAIN
ELECTRIC POTENTIAL
ELECTROENCEPHALOGRAPHY
NERVOUS SYSTEM
PARABIOSIS
PHYSIOLOGY
RADIATION DOSES
RADIATION EFFECTS
RADIATION SICKNESS
RATS
RECORDING SYSTEMS