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EXPERIMENTAL STUDIES ON THE SARCOMA FORMATION WITH THORIUM DIOXIDE SOL (THOROTRAST) (in Japanese)

Journal Article · · Fukuoka Igaku Zasshi (Japan)
OSTI ID:4057899
In view of reports of malignant tumors resulting from the use of Thorotrast for arteriography in man, experiments were conducted in rats injected with colloidal ThO/sub 2/. Granulomas developed after subcutaneous or intraperitoneal injections of ThO/sub Z/, and in 16 to 23% of the rats, depending on the site of injection, sarcomas developed from the granulomas. The highest percentage of malignancy (23%) was noted after subcuthneous injection, and 60% of rats so injected died within one year. (BBB)
Research Organization:
Kyushu Univ., Fukuoka
NSA Number:
NSA-18-017518
OSTI ID:
4057899
Journal Information:
Fukuoka Igaku Zasshi (Japan), Journal Name: Fukuoka Igaku Zasshi (Japan) Vol. Vol: 52; ISSN FKIZA
Country of Publication:
Country unknown/Code not available
Language:
Japanese

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