Lipid Mobilization in X-Irradiated Rabbits
The effects of lethal total-body x irradiation on various plasma lipid fractions and the degree of peripheral lipid mobilization were investigated in rabbits. Peripheral lipid mobilization was measured by the decrease in lipid concentration of a characteristic fat depot and the plasma free fatty acid response. Plasma phospholipid, free and ester cholesterol, and triglycerides were significantly increased after x irradiation. However, plasma free fatty acids were unaltered. Finally, a similar degree of lipid depletion from the adipose depot was noted in both control and x-irradiated animals, denoting that increased peripheral lipid mobilization was not a factor in the etiology of postirradiation hyperlipemia.
- Research Organization:
- Univ. of Tennessee Medical Units, Memphis
- Sponsoring Organization:
- USDOE
- NSA Number:
- NSA-15-022127
- OSTI ID:
- 4047868
- Journal Information:
- Radiation Research, Journal Name: Radiation Research Journal Issue: 6 Vol. 14; ISSN 0033-7587
- Publisher:
- Radiation Research Society
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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