EFFECT OF HIGH CALCIUM INTAKE ON STRONTIUM$sup 85$ METABOLISM IN MAN

Journal Article · Sat Jul 01 04:00:00 EDT 1961 · Journal of Clinical Investigation (U.S.)

DOI:https://doi.org/10.1172/JCI104364· OSTI ID:4046011

Spencer, H; Li, M; Samachson, J

The effect of high Ca intake of varying duration was studied on Sr/sup 8/ /sup 5/ metabolism in 14 patients under controlled dietary conditions. The Ca intake of 10 patients was approximately 10 times as high during high intake as during low intake. Tracer doses of Sr/sup 8//sup 5/ were given orally or intravenously in separate studies during-low and high Ca intake to the same subject. The intestinal absorption of orally administered tracer doses of Sr/sup 8//sup 5/ was of similar magnitude during low and high calcium intake in 7 of 11 patients and was lower in 4 patients during high than during low Ca intake. The addition of Ca to the diet resulted in increased urinary excretion of Ca in most patients. This increase was accompanied by a somewhat higher excretion of Sr/sup 8//sup 5/ after intravenous doses in 4 of 6 patients, while in general, no increase of urinary Sr/sup 8//sup 5/ excretion occurred when Sr/sup 8//sup 5/ was given orally. (auth)

• Research Organization: Montefiore Hospital, New York
• Sponsoring Organization: USDOE
• NSA Number: NSA-15-021975
• OSTI ID: 4046011
• Journal Information: Journal of Clinical Investigation (U.S.), Journal Name: Journal of Clinical Investigation (U.S.) Vol. Vol: 40; ISSN JCINA
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

ABSORPTION
BIOLOGY AND MEDICINE
CALCIUM
DIET
INTESTINE
MAN
METABOLISM
STRONTIUM 85
TRACER TECHNIQUES
URINE