STRONTIUM-90 BALANCES IN MAN

Journal Article · Sat Jun 01 04:00:00 EDT 1963 · Clinical Science (England) Changed to Clin. Sci. Mol. Med.

OSTI ID:4659857

Spencer-Laszlo, H; Samachson, J; Hardy, Jr, E P; Rivera, J

Metabolism of Sr/sup 90/ of dietary origin was studied under controlled metabolic and dietary conditions in 12 student nurses during a relatively high Ca intake. No Sr/sup 90/ was administered, other than that present in the diet, which was assayed by low-level BETA counting of the Y/sup 90/ daughter product. Sr/sup 90/ content of urine and stool was also determined by lowlevel counting. Balances of Sr/sup 90/ and of Ca were measured on 8-day pools of urine, stool, and on aliquots of the diet. The Sr/sup 90/ content of milk was hlgher in December 1959 (11.4 mu mu c/day, or per 960 ml) than in the subsequent 5 months (9.3 mu mu c from January to May 1980) and was lowest in June 1980 (8.5). Sr/ sup 90/ content of milk had decreased in March 1981 (8.2). Sr/sup 90/ content of the total daily diet exclusive of milk was constant from December 1959 to June 1960 and ranged from 3.5 to 4.3 mu mu c/day. The Sr/sup 90//Ca ratio of the diet was higher than that of urine in all persons studied except one. Average dietary Sr/sup 90//Ca ratio of all volunteers was 1.12, while the urinary Sr/sup 90//Ca ratio was 0.94. The fecal Sr/sup 90//Ca ratio was hlgher than that of urine in 10 of 12 subjects and averaged 1.49. The average percent absorption expressed in percent of the dietary intake was considerably higher for Ca (40.8%) than for Sr/sup 90/ (15.8%), and the average absorption ratio of Ca/Sr/sup 90/ was 2.58. The average urinary Sr/sup 90/ excretion represented 9.1% of the average Sr/sup 90/ intake. A significant correlation was noted between the urinary excretion of Sr/sup 90/, expressed in percent of the intake, and the urinary Ca excretion; however, correlation between balances of Ca and Sr/sup 90/ was not significant. The urinary Sr/sup 90/ excretion of 10 other volunteers of similar age who received a low-Ca diet without the addition of milk was about 1/3 the value for the present group. The results were in good agreement with data obtained with tracer doses of Sr/sup 85/ in man. The major portion of Sr/sup 90/ contained in food passed through the intestine, and on an average only 18% of the dietary Sr/sup 90/ intake was absorbed. At the time of this study the average Sr/ sup 90/ intake in New York City was similar to that of the analyzed diet, so that these volunteers may be representative of the general population in this age group (18-21 yr). (BBB)

• Research Organization: Veterans Administration Hospital, Hines, Ill.
• NSA Number: NSA-17-035421
• OSTI ID: 4659857
• Journal Information: Clinical Science (England) Changed to Clin. Sci. Mol. Med., Journal Name: Clinical Science (England) Changed to Clin. Sci. Mol. Med. Vol. Vol: 24; ISSN CSCIA
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

AGE
BETA DETECTION
BIOLOGY AND MEDICINE
CALCIUM
CONTROL
DIET
INTESTINE
MAN
METABOLISM
MILK
POPULATIONS
QUANTITY RATIO
STRONTIUM 85
STRONTIUM 90
URINE
YTTRIUM 90