Immunocompetent cells in man. III. The killer cell activity of normal circulating lymphocytes
Journal Article
·
· Clin. Immunol. Immunopathol., v. 4, no. 2, pp. 286-290
OSTI ID:4045236
Circulating lymphocytes obtained from normal individuals are capable of inducing cytotoxic death of $sup 51$Cr-labeled rabbit spleen target cells in culture. An incubation time of 16 to 24 hr was sufficient to permit optimal cytolysis of the target cells. The cytotoxic activity was a property of the living cells as neither sonicated nor irradiated human cells displayed cytotoxic activity. The data suggest that this culture system may provide a rapid indicator for the immunocompetence of circulating human lymphocytes, insofar as their ability to express cell-mediated immunity is concerned. (auth)
- Research Organization:
- Univ. of Ottawa
- NSA Number:
- NSA-33-029628
- OSTI ID:
- 4045236
- Journal Information:
- Clin. Immunol. Immunopathol., v. 4, no. 2, pp. 286-290, Journal Name: Clin. Immunol. Immunopathol., v. 4, no. 2, pp. 286-290; ISSN CLIIA
- Country of Publication:
- United States
- Language:
- English
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