DISTRIBUTION OF Ce$sup 144$-Pr$sup 144$ IN MICE, AND PATHOLOGICAL OBSERVATIONS
Journal Article
·
· Nippon Igaku Hoshasen Gakkai Zasshi (Japan)
OSTI ID:4045076
Three mu c/g of Ce/sup 1//sup 4//sup 4/-Pr/sup 1//sup 4//sup 4/ were injected into the per itoneal cavity of male mice, 18 g in body weight. The LD/ sub 1//sub 0//sub 0/ was 27 days and the LD/sub 5//sub 0/ was 21 days. Percentage of uptake of Ce/sup 1//sup 4//sup 4/-Pr/sup 1//sup 4//sup 4/ was highest in the bone and the bone marrow and next in the liver. The exposure dose was highest in the spleen and then in the testis and liver. Generally speaking, pathological changes were most severe in the mice which died 2 to 3 weeks after injection. Some recovery was seen 4 weeks after injection. The loss of spermatogenesis is worthy of attention. (Absts. Japan. Med., 1: No. 7, 1960.)
- Research Organization:
- Tokyo Univ.
- NSA Number:
- NSA-15-022104
- OSTI ID:
- 4045076
- Journal Information:
- Nippon Igaku Hoshasen Gakkai Zasshi (Japan), Journal Name: Nippon Igaku Hoshasen Gakkai Zasshi (Japan) Vol. Vol: 19; ISSN NHGZA
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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