EFFECTS OF COMBINED USE OF X-RAY AND RIBONUCLEIC ACID (COMBINED EFFECTS OF RADIATION AND CHEMICALS, 11Th REPORT)
The effects of combined use of RNA and x rays on sarcoma cells are reported. About 3 to 4 days after trsnsplantation, rats with MTK-111 sarcoma were exposed to x irradiation of 200 r. RNA was injected into the peritoneal cavity. After the injection of RNA, the mitotic index appeared appreciably increased, associated with the augmentation of dividing cells in each phase. The injection-of RNA before x irradiation caused a marked decrease of mitotic cells and produced a large number of abnormal chromosomes. The effect was considerably stronger thsn that of the administration of x rays alone. (Abstr. Japan. Med., 1: No. 1, 1960) A hematological follow-up of x-ray and isotope workers at Tohoku University is reported. The workers of the nonmedical departments and research institutes used radioactive isotopes of not more than a few mc per day and did not manipulate high voltage x-ray generators. They had no marked changes in their blood pictures, as they were exposed to very low levels of radiation. The total leukocyte count in the members of the Dept. of Radiology and x-ray Technicians in Miyagi Prefecture was generally decreased due to a low neutrophile count. With reduction of exposure, their leukocyte counts tended to improve slowly. Therefore, a decrease in leukocyte count depends on the dose rather than on the length of duration of radiation work. The workers with a total leukocyte count below 4000 gave the impression of having a fixed and unfluctuating leukocyte level. It was difficult to lead them to recovery. The leukocyte pictures plotted on the hemogram showed a decrease in neutrophils and monocytes and an increase in lymphocytes. However, lymphocyte and monocyte counts tended to increase gradually in each examination. As the total leukocyte counts tended to improve the leukocyte picture remained stationary. (Abstr. Japan Med., 1: No. 8, 1961)
- Research Organization:
- Hokkaido Univ., Sapporo
- NSA Number:
- NSA-15-022089
- OSTI ID:
- 4044216
- Journal Information:
- Nippon Igaku Hoshasen Gakkai Zasshi (Japan), Journal Name: Nippon Igaku Hoshasen Gakkai Zasshi (Japan) Vol. Vol: 19; ISSN NHGZA
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
Similar Records
EXPERIMENTAL STUDIES ON THE COMBINED EFFECT OF RADIATION AND VARIOUS CHEMICALS ON MITOTIC CELLS. XXIV. EFFECT OF COMBINED USE OF X-RAYS AND CITRIC ACID
BLOOD PICTURES OF RADIOLOGICAL WORKERS. II. BLOOD PICTURE IN OCCUPATIONAL RADIATION HAZARDS