THE PROTECTIVE EFFECT OF CYSTEAMINE AGAINST GENETIC DAMAGES BY X-RAYS IN SPERMATOZOA FROM MICE
Males from the CBA strain of mice were given intraperitoneal injections with cysteamine or physiological saline, followed by 0 (control), 300, or 600 r of x rays. The males were each subsequently mated to 3 virgin CBA females for a period of 7 days. The females were killed on the sixteenth or the twentieth day after start of mating. The uteri were examined for live and dead embryos; 5145 embryos were analyzed. The rate of death was significantly lower among the offspring of males which were given cysteamine rather than saline prior to irradiation. The cysteamine reduced the rate of mutations to 75% of that in males given physiological saline only. (auth)
- Research Organization:
- Research Inst. of National Defense, Sundbyberg, Sweden
- Sponsoring Organization:
- USDOE
- NSA Number:
- NSA-15-022174
- OSTI ID:
- 4042384
- Journal Information:
- Radiation Research, Journal Name: Radiation Research Vol. Vol: 14
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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