BOUND AND SOLUBLE DEOXYPOLYNUCLEOTIDES IN THE TISSUES OF IRRADIATED RABBITS
The content of protein-bound DNA and of soluble desoxypoIynucleotides was studled in the lymphoid tissue of the appendix, in the spleen, bone marrow, small intestinal mucosa, liver, and blood of rabbits. The highest concentration of bound DNA was found in metabolically active tissues. Irradiation of rabbits with the dose of 1000 r resulted in a decrease in the protein-bound DNA by 60 to 40% in the bone marrow, spleen, and the appendix; in the small intestinal mucosa, the decrease was 20%. The quantity of free DNA in these tissues increased considerably and reached a maximum in four hours. In the liver and blood, no signifleant changes in the content of free and protein-bound DNA were found. (auth)
- Research Organization:
- Originating Research Org. not identified
- NSA Number:
- NSA-15-016821
- OSTI ID:
- 4039089
- Journal Information:
- Biochemistry (U.S.S.R.) (English Translation), Journal Name: Biochemistry (U.S.S.R.) (English Translation) Vol. Vol: 25
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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