PROGRESSIVE ALTERATION OF SERUM PROTEINS IN RATS SEVERAL MONTHS AFTER AN ACUTE OR PROTRACTED IRRADIATION

Journal Article · Thu Aug 01 04:00:00 EDT 1963 · Intern. J. Radiation Biol.

DOI:https://doi.org/10.1080/09553006314551041· OSTI ID:4037288

Reuter, A; Ghys, R

Sprague-Dawley rats six- to eight-weeks-old were given ₆₀Co gamma irradiation in doses ranging from immediately sublethal to the LD₅₀. One group of animals kept at 6 deg C for one month prior to irradiation was able to survive wholebody doses up to 1800 rads. Microdetermination of total serum proteins made in normal and irradiated rats by the Biuret method yielded no significant variations in the total serum proteins of any one group. However, the gamma -globulin fraction increased markedly in most irradiated rats. Cold acclimatization did not make signlficant alterations in the serum-protein pattern of irradiated rats, and no relation between magnitude of radiation dose and protein changes was observed in the dose-range used. (H.M.G.)

• Research Organization: Universite, Laval, Que.
• Sponsoring Organization: USDOE
• NSA Number: NSA-18-019642
• OSTI ID: 4037288
• Journal Information: Intern. J. Radiation Biol., Journal Name: Intern. J. Radiation Biol. Vol. Vol: 7
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

AGE
BIOLOGY AND MEDICINE
BLOOD SERUM
COBALT 60
GAMMA RADIATION
GLOBULINS
IRRADIATION
LETHAL DOSE
PERFORMANCE
PROTEINS
QUALITATIVE ANALYSIS
QUANTITATIVE ANALYSIS
RADIATION DOSES
RADIATION EFFECTS
RATS
SURVIVAL TIME
TEMPERATURE
VARIATIONS