EFFECT OF RADIATIONS ON THE NUCLEIC ACID METABOLISM IN MICE. III. COMPARISON OF X-RAY AND Co$sup 60$ GAMMA-RAY ON NUCLEIC ACID CONTENT OF THE THYMUS, SPLEEN AND TESTES

Journal Article · Thu Jan 01 04:00:00 EST 1959 · Nippon Igaku Hoshasen Gakkai Zasshi (Japan)

OSTI ID:4034785

Yamamoto, G

Male and female mice of C/sub 3/H strain were used. One group was irradiated by a single whole-body exposure of x rays (160 kvp) or Co/sup 60/ gamma rays of 50 r and 200 r under the same minute intensity. The other group was irradiated by x rays (150 kvp) 33.4 r in 3 min and 22 sec a day for 6 days, and gamma rays (Co/sup 60/ 33.4 r in 22 hours a day for 6 days. The total dose of both cases reached 200 r. After irradiation the nucleic acid metabolism and the amount of nucleic acid was measured. In single whole-bcdy irradiation of the same doses, x ray was more effective on nucleic acid metabolism in the spleen than Co/sup 60/ gamma -ray irradiation. The difference was exaggerated particularly in the case of 50 r exposure. However, no significant difference resulted in the thymus after x ray or Co/sup 60/irradiation. In a case of fractionated doses x ray also appeared more effective than Co/sup 60/ gamma ray. It was concluded that, as the dose rate was different in x ray and Co/sup 60/ irradiation, the time factor strongly influenced the effectiveness of irradiation. (Absts. Japan. Med., 1: No. 6, 1961)

• Research Organization: Kyoto Univ.
• NSA Number: NSA-15-023322
• OSTI ID: 4034785
• Journal Information: Nippon Igaku Hoshasen Gakkai Zasshi (Japan), Journal Name: Nippon Igaku Hoshasen Gakkai Zasshi (Japan) Vol. Vol: 19; ISSN NHGZA
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

BIOLOGY AND MEDICINE
BODY
COBALT 60
GAMMA RADIATION
GLANDS
GONADS
IRRADIATION
METABOLISM
MICE
NUCLEIC ACIDS
QUANTITY RATIO
RADIATION DOSES
RADIATION EFFECTS
SPLEEN
THYMUS
WHOLE-BODY IRRADIATION
X RADIATION