THE BEHAVIOR OF ACID PHOSPHATASE, THE UNSPECIFIC ESTERASE, THE E-600- RESISTANT ESTERASE, AND THE LIPOIDS IN THE ADRENAL GLAND OF GUINEA PIGS AFTER WHOLE-BODY AS WELL AS LOCAL X-RAY IRRADIATION (in German)
Journal Article
·
· Strahlentherapie (West Germany)
OSTI ID:4023082
The behavior of lipids, of nonspecific esterases, of E600-resistant esterase, and of the acid phosphatase in the adrenal gland of healthy guinea pigs as well as after totalbody irradiation and a local irradiation with doses of 400 r each was studied. A decrease of lipids proportional to the radiation sickness was found in the total-body-irradiated animals; a smaller loss of lipids was found in animals irradiated locally. A decrease of activity of the nonspecific esterases could be determined after x-ray irradiation, which is probably connected with disturbances in the lipid metabolism. There was a considerable increase in activity of the acid phosphatase that was connected with damage to the lysosomes releasing the enzymes. An increased appearance of coarse granules distributed patternlike seemed to be the result of degenerative events in the cytoplasm. The tendency of the E-600-resistant esterase to increase in the adrenal glands after x-ray irradiation pointed out a proteolytic part of this enzyme. It was assumed, that the changes are caused by a direct effect of x rays on the adrenal glands and are indirectly accelerated by extraadrenal noxae (decay products of protein and electrolytic disturbances in the total organism.). (auth)
- Research Organization:
- Silesian Mediziniche Akademie, Zabrze, Poland
- NSA Number:
- NSA-18-019710
- OSTI ID:
- 4023082
- Journal Information:
- Strahlentherapie (West Germany), Journal Name: Strahlentherapie (West Germany) Vol. Vol: 123; ISSN STRAA
- Country of Publication:
- Country unknown/Code not available
- Language:
- German
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