ON INFLUENCE OF IONIZING IRRADIATION UPON THE FORMATION OF ANTIBODIES IN A COMBINED ADMINISTRATION OF VARIOUS ANTIGENS (in Russian)
Irradiation of rabbits prior to intravenous injection of cell antigens (erythrocytes, bacteria) was shown to suppress considerably the formation of antibodies. When artigens were administered prior to irradiation, the formation of agglutinins was not suppressed, while that of hemolysin was partly inhibited. Twofold immunization of the rabbits with similar antigens (erythrocytes or bacteria) stimulates the formation of antibodies. The subsequent irradiation offers an inhibiting effect only on repeated antigen stimulation. Immunization of normal rabbits with erythrocytes, and then with bacteria, stimulates the formation of agglutinins. The subsequent irradiation considerably suppresses the production of agglutinins. When nonirradiated rabbits are injected with bacteria and then with erythrocytes, the production of hemolysins is inhibited. The similar inhibitory effect in the production of hemolysins is also observed when the rabbits are irradiated after such immunization. (auth)
- Research Organization:
- Originating Research Org. not identified
- NSA Number:
- NSA-18-019735
- OSTI ID:
- 4022714
- Journal Information:
- Vopr. Radiobiol., Akad. Nauk Arm. SSR, Sektor Radiobiol., Sb. Tr., Vol. Vol: 2; Other Information: Orig. Receipt Date: 31-DEC-64
- Country of Publication:
- Country unknown/Code not available
- Language:
- Russian
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