Chromosome aberrations in irradiated human subjects

Journal Article · Sun Mar 01 04:00:00 EST 1964 · Annals of the New York Academy of Sciences

DOI:https://doi.org/10.1111/j.1749-6632.1964.tb53579.x· OSTI ID:4019400

Bender, Michael A.

Somatic chromosomes were studied in men 29 months after accidental exposure to whole-body irradiation. Using the peripheral leukocyte technique of Moorhead, rings, dicentrics, and deletions were observed in all but the lowest dose case. A second study of leukocytes of the men made 42 months after the accident yielded vintually the same results as the 29-month study. Peripheral blood samples were studied at four hours and at 2, 4, and 10 weeks in men exposed to mixed gamma and neutron irradiation. In the first three samples, the aberration frequencies remained approximately constant, but dropped in the last sample. Deletion and dicentric frequencies are presented. A third group of men received whole-body irradiation in an incident involving only gamma radiation. Samples were analyzed three days after the accident for deletion and dicentric frequencies.

• Research Organization: Oak Ridge National Lab., Tenn.
• Sponsoring Organization: USDOE
• NSA Number: NSA-18-019582
• OSTI ID: 4019400
• Journal Information: Annals of the New York Academy of Sciences, Journal Name: Annals of the New York Academy of Sciences Journal Issue: 1 Vol. 114; ISSN 0077-8923
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
ACCIDENTS
BLOOD
BODY
CHROMOSOMES
CYTOLOGY
GAMMA RADIATION
IRRADIATION
LEUCOCYTES
MAN
NEUTRON BEAMS
RADIATION DOSES
RADIATION EFFECTS
RADIOSENSITIVITY
SAMPLING
TISSUES
VARIATIONS