DIURNAL PERIODICITY OF MITOSIS IN MICE AFTER IRRADIATION WITH $gamma$-RAYS

Journal Article · Sun Mar 01 04:00:00 EST 1964 · Bull. Exptl. Biol. Med. (U.S.S.R.) (English Transl.)

DOI:https://doi.org/10.1007/BF00800215· OSTI ID:4019007

Kosichenko, L P

A study was made of the effect produced by ionizing radiation (190 and 400 r) on the 24-hr periodicity of mitotic activity of the mouse corneal epithelium. As noted, the 24-hr mitotic rhythm was retained on the 5th postirradiation day (doses of l90 and 400 r being used). The time of the maximal (8 A.M.) and the minimal (8 P.M.) number of mitoses in the corneal epithelium of experimental mice coincided with control indices. The difference between the maximal and minimal mitotic activity in the two experiments was highly signiticant. The range of the 24-hr variations of the number of mitoses showed no significant change in the experimental animals. After irradiation of mice by a dose of 400 r, there was a tendency to a rise of the mean 24-hr intensity of cellular multiplication. (auth)

• Research Organization: Inst. of Experimental Pathology and Therapy, Sukhumi USSR
• Sponsoring Organization: USDOE
• NSA Number: NSA-18-019610
• OSTI ID: 4019007
• Journal Information: Bull. Exptl. Biol. Med. (U.S.S.R.) (English Transl.), Journal Name: Bull. Exptl. Biol. Med. (U.S.S.R.) (English Transl.) Vol. Vol: 55
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

BIOLOGY AND MEDICINE
GAMMA RADIATION
IRRADIATION
MICE
MITOSIS
RADIATION DOSES
RADIATION EFFECTS
STANDARDS
TESTING
TISSUES
VARIATIONS