RADIATION EFFECTS ON THE MITOTIC CYCLE OF CORNEA AND INTESTINE EPITHELIA IN MICE

Journal Article · Tue Jan 01 04:00:00 EST 1963 · Radiobiologiya (U.S.S.R.) For English translation see Radiobiology (Engl. Transl.)

OSTI ID:4023389

Chumak, M G

Effects of whole-body irradiation of mice (400-r doses) on mitotic cycles in corneal and intestinal epithelia were investigated using H/sub 3/- thymidine autoradiography. It was found that the interphase period in corneal epithelium is 6.5 times that in intestinal epithelium. Radioinduced mitotic changes in G/sub 2/-M and G/sub 1/--S blocks and disturbances in DNA synthesis were observed in both tissues. During the restorative period the G/sub 2/--M biock recovers first, DNA synthesis is normalized next, and the G/sub 2/--S block recovers last. In corneal epithelium the above processes are slower than in the intestine. (R.V.J.)

• Research Organization: Inst. of Radiation Physics, Chemistry, And Biology, Moscow
• NSA Number: NSA-18-019689
• OSTI ID: 4023389
• Journal Information: Radiobiologiya (U.S.S.R.) For English translation see Radiobiology (Engl. Transl.), Journal Name: Radiobiologiya (U.S.S.R.) For English translation see Radiobiology (Engl. Transl.) Vol. Vol: 3; ISSN RADOA
• Country of Publication: Country unknown/Code not available
• Language: Russian

Related Subjects

ANIMAL CELLS
BIOLOGY AND MEDICINE
BODY
CORNEA
DNA
EYES
INTESTINE
IRRADIATION
LABELLED COMPOUNDS
METABOLISM
MICE
MITOSIS
NUCLEIC ACIDS
ORGANIC NITROGEN COMPOUNDS
RADIATION DOSES
RADIATION EFFECTS
RADIATION INJURIES
RADIOAUTOGRAPHY
RECOVERY
THYMIDINE
TISSUES
TRACER TECHNIQUES
TRITIUM
VARIATIONS