EFFECT OF IONIZING RADIATIONS ON TISSUE METABOLISM

Journal Article · Fri Jan 01 04:00:00 EST 1960 · Nippon Igaku Hoshasen Gakkai Zasshi (Japan)

OSTI ID:4010377

Yokota, G

An inhibition of tissue respiration in rats, caused by single whole-body x irradiation, was most severe in the spleen followed by that in the liver and kidney. The tissue respiration of the cerebral cortex was mostly accelerated. The respiration of the liver, spleen, and kidney cells was more hindered by divided whole-body irradiations than by a single radiation. The whole-body radiation of a small amount of x rays (1 r x 3) inhibited the tissue respiration of the spleen. The x irradiation did not inhibit the tissue respiration of extirpated organs (liver, spleen, kidney). The respiration of the liver cells was strongly inhibited by the x irradiation on the hepatic region. After the single radiation, however, a transient acceleration was observed in a week but none after the divided radiations. The skin tissue respiration of the hepatic region was intsnsely hindered by the x irradiation of this region. The inhibition of tissue respiration caused by x irradiation was prevented to a certain extent by previous administration of a substance with the SH radical, particularly by cysteine, glutatbione and methionine. (Abstr. Japan Med., 1: No. 9, 1961)

• Research Organization: Kyoto Univ.
• NSA Number: NSA-15-025895
• OSTI ID: 4010377
• Journal Information: Nippon Igaku Hoshasen Gakkai Zasshi (Japan), Journal Name: Nippon Igaku Hoshasen Gakkai Zasshi (Japan) Vol. Vol: 19; ISSN NHGZA
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

AMINO ACIDS
ANIMAL CELLS
BIOLOGY AND MEDICINE
BODY
BRAIN
CYSTEINE
FREE RADICALS
IRRADIATION
KIDNEYS
LIVER
METABOLISM
OXYGEN
RADIATION EFFECTS
RATS
SKIN
SPLEEN
TISSUES
WHOLE-BODY IRRADIATION
X RADIATION