Osmium-catalyzed asymmetric dihydroxylation of cyclic cis-disubstituted olefins

Journal Article · Fri Nov 18 04:00:00 EST 1994 · Journal of Organic Chemistry

DOI:https://doi.org/10.1021/jo00102a008· OSTI ID:379292

Wang, Zhi-Wang; Kakiuchi, Kiyomi; Sharpless, K B ^[1]

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1. Scripps Research Institute, La Jolla, CA (United States)

A new class of cis-disubstituted olefins has been found to give good enantioselectives in the asymmetric dihydroxylation reaction using the standard PHAL and PYR ligands. All of the olefins are conjugated, and the reacting double bond is endocyclic in a 5-, 6-, 7-, or 8-membered ring. 2 figs., 1 tab.

• Sponsoring Organization: USDOE
• OSTI ID: 379292
• Journal Information: Journal of Organic Chemistry, Journal Name: Journal of Organic Chemistry Journal Issue: 23 Vol. 59; ISSN 0022-3263; ISSN JOCEAH
• Country of Publication: United States
• Language: English

Related Subjects

40 CHEMISTRY
ALKENES
CATALYTIC EFFECTS
HYDROXYLATION
OSMIUM COMPOUNDS
STEREOCHEMISTRY