The human topoisomerase I gene promoter is regulated by NF-IL6
Journal Article
·
· Molecular and Cellular Biology
- Universitaet Konstanz (Germany)
This report describes the expression of the human DNA topoisomerase I (hTOP1) gene in HeLa cells and in adenovirus-transformed cells. Specific promoter-binding proteins are present in HeLa cells which resemble the nuclear factor for interleukin-6 expression (NF-IL6). It was also found that NF-IL6 can substitute for the viral regulatory protein E1A in adenovirus infection. 49 refs., 10 figs.
- Sponsoring Organization:
- USDOE
- OSTI ID:
- 379254
- Journal Information:
- Molecular and Cellular Biology, Journal Name: Molecular and Cellular Biology Journal Issue: 12 Vol. 15; ISSN 0270-7306; ISSN MCEBD4
- Country of Publication:
- United States
- Language:
- English
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