Ion Transport in Self-Assembled Peptoid Membranes with Carbon Nanotube Porin Channels

Saraswat, Mohit; Chakma, Progyateg; Zhang, Shuai; Mondarte, Evan Angelo Quimada; Chen, Chun-Long; Noy, Aleksandr

doi:10.1021/acs.nanolett.5c04253

Ion Transport in Self-Assembled Peptoid Membranes with Carbon Nanotube Porin Channels

Journal Article · Wed Nov 19 00:00:00 EST 2025 · Nano Letters

DOI:https://doi.org/10.1021/acs.nanolett.5c04253· OSTI ID:3011782

Saraswat, Mohit ^[1]; Chakma, Progyateg ^[2]; ^[3]; ^[2]; ^[3]; ^[1]

Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States); Univ. of California, Merced, CA (United States)
Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)
Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Univ. of Washington, Seattle, WA (United States)

Artificial membranes that combine high ionic selectivity with mechanical robustness remain a key challenge for next-generation separation technologies. Here, we report ion transport measurements in biomimetic membranes composed of crystalline peptoid nanosheets co-assembled with carbon nanotube porins (CNTPs). Pure peptoid sheets formed defect-free, ion-impermeable membranes, which were then suspended over small SiN_x nanopore apertures for ion transport measurements. Incorporation of CNTPs into the peptoid sheet matrix made these membranes ion permeable, with ion conductance values consistent with ion transport through individual and multiple carbon nanotube channels. In conclusion, the modularity and molecular order of peptoid membranes, combined with the exceptional conductance properties of CNTPs, position this platform as a versatile framework for assembling programmable, selective, and robust nanofluidic membranes that can bridge the performance gap between biological and synthetic membrane materials.

View Accepted Manuscript (DOE)

Research Organization:: Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)

Sponsoring Organization:: USDOE National Nuclear Security Administration (NNSA); USDOE Office of Science (SC), Basic Energy Sciences (BES)

Grant/Contract Number:: AC05-76RL01830; AC52-07NA27344

OSTI ID:: 3011782

Report Number(s):: LLNL--JRNL-2010459

Journal Information:: Nano Letters, Journal Name: Nano Letters Journal Issue: 48 Vol. 25; ISSN 1530-6992; ISSN 1530-6984

Publisher:: American Chemical SocietyCopyright Statement

Country of Publication:: United States

Language:: English

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