Co-Assembly of Carbon Nanotube Porins into Biomimetic Peptoid Membranes

Zhang, Shuai; Hettige, Jeevapani J.; Li, Yuhao; Jian, Tengyue; Yang, Wenchao; Yao, Yun‐Chiao; Zheng, Renyu; Lin, Zhixing; Tao, Jinhui; De Yoreo, James J.; Baer, Marcel; Noy, Aleksandr; Chen, Chun‐Long

doi:10.1002/smll.202206810

Co-Assembly of Carbon Nanotube Porins into Biomimetic Peptoid Membranes

Journal Article · Tue Feb 21 00:00:00 EST 2023 · Small

DOI:https://doi.org/10.1002/smll.202206810· OSTI ID:2203344

Zhang, Shuai ^[1]; Hettige, Jeevapani J. ^[2]; Li, Yuhao ^[3]; Jian, Tengyue ^[2]; ^[2]; Yao, Yun‐Chiao ^[4]; Zheng, Renyu ^[5]; Lin, Zhixing ^[5]; Tao, Jinhui ^[2]; De Yoreo, James J. ^[1]; Baer, Marcel ^[2]; ^[4]; ^[1]

Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); University of Washington, Seattle, WA (United States)
Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)
Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States); University of California, Merced, CA (United States)
University of Washington, Seattle, WA (United States)

Robust and cost-effective membrane-based separations are essential to solving many global crises, such as the lack of clean water. Even though the current polymer-based membranes are widely used for separations, their performance and precision can be enhanced by using a biomimetic membrane architecture that consists of highly permeable and selective channels embedded in a universal membrane matrix. Researchers have shown that artificial water and ion channels, such as carbon nanotube porins (CNTPs), embedded in lipid membranes can deliver strong separation performance. However, their applications are limited by the relative fragility and low stability of the lipid matrix. In this work, we demonstrate that CNTPs can co-assemble into two-dimension (2D) peptoid membrane nanosheets, opening up a way to produce highly programmable synthetic membranes with superior crystallinity and robustness. A combination of molecular dynamics (MD) simulations, Raman spectroscopy, X-ray diffraction (XRD), and atomic force microscopy (AFM) measurements to verify the co-assembly of CNTP and peptoids are used and show that it does not disrupt peptoid monomer packing within the membrane. In conclusion, these results provide a new option for designing affordable artificial membranes and highly robust nanoporous solids.

View Accepted Manuscript (DOE)

Research Organization:: Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)

Sponsoring Organization:: National Science Foundation (NSF); USDOE; USDOE National Nuclear Security Administration (NNSA); USDOE Office of Science (SC), Basic Energy Sciences (BES). Materials Sciences & Engineering Division (MSE); USDOE Office of Science (SC), Basic Energy Sciences (BES). Scientific User Facilities (SUF)

Grant/Contract Number:: AC02-05CH11231; AC05-76RL01830; AC52-07NA27344

OSTI ID:: 2203344

Alternate ID(s):: OSTI ID: 1975140

Report Number(s):: LLNL--JRNL-841947; 1063537

Journal Information:: Small, Journal Name: Small Journal Issue: 21 Vol. 19; ISSN 1613-6810

Publisher:: WileyCopyright Statement

Country of Publication:: United States

Language:: English

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