Genetic approaches for identifying kinetochore components in Saccharomyces cerevisiae
Conference
·
OSTI ID:28434
- John Hopkins Univ. Medical School, Baltimore, MD (United States)
A fundamental aspect of the cell division cycle is the chromosome cycle in which each of the chromosomal DNA molecules undergoes a series of morphological changes and complex movements to ensure faithful distribution at mitosis. The gene products responsible for execution of the chromosome cycle include structural components, such as those that assemble into the mitotic spindle apparatus, and regulatory components, such as those that coordinate the ordered series of events leading to chromosome segregation within the cell cycle. We have been taking several genetic approaches to identify genes encoding determinants critical to the chromosome cycle in the budding yeast, S. cerevisiae.
- OSTI ID:
- 28434
- Report Number(s):
- CONF-9210475--Cond.
- Country of Publication:
- United States
- Language:
- English
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