Confocal Raman Microscopy of Optical-Trapped Particles in Liquids

Cherney, Daniel P.; Harris, Joel M.

doi:10.1146/annurev-anchem-070109-103404

Confocal Raman Microscopy of Optical-Trapped Particles in Liquids

Journal Article · Mon Mar 08 23:00:00 EST 2010 · Annual Review of Analytical Chemistry

DOI:https://doi.org/10.1146/annurev-anchem-070109-103404· OSTI ID:2480574

Cherney, Daniel P. ^[1]; Harris, Joel M. ^[2]

University of Utah, Salt Lake City, UT (United States); University of Utah
University of Utah, Salt Lake City, UT (United States)

The in situ analysis of small, dispersed particles in liquids is a challenging problem, the successful solution to which influences diverse applications of colloidal particles in materials science, synthetic chemistry, and molecular biology. Optical trapping of small particles with a tightly focused laser beam can be combined with confocal Raman microscopy to provide molecular structure information about individual, femtogram-sized particles in liquid samples. In this study, we consider the basic principles of combining optical trapping and confocal Raman spectroscopy, then survey the applications that have been developed through the combination of these techniques and their use in the analysis of particles dispersed in liquids.

View Accepted Manuscript (DOE)

Research Organization:: University of Utah, Salt Lake City, UT (United States)

Sponsoring Organization:: USDOE Office of Science (SC), Basic Energy Sciences (BES). Chemical Sciences, Geosciences & Biosciences Division (CSGB); National Science Foundation (NSF)

Grant/Contract Number:: FG03-93ER14333

OSTI ID:: 2480574

Journal Information:: Annual Review of Analytical Chemistry, Journal Name: Annual Review of Analytical Chemistry Journal Issue: 1 Vol. 3; ISSN 1936-1327

Publisher:: Annual ReviewsCopyright Statement

Country of Publication:: United States

Language:: English

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Liposomal Drug Delivery Systems: An Update Review Samad, Abdus; Sultana, Y.; Aqil, M. Current Drug Delivery, Vol. 4, Issue 4 https://doi.org/10.2174/156720107782151269	journal	October 2007

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37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
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Confocal Raman Microscopy of Optical-Trapped Particles in Liquids

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