On the processing pf piecewise-constant signals by hierarchical models with application to single ion channel currents
Conference
·
OSTI ID:224109
- State Univ. of New York, Stony Brook, NY (United States). Dept. of Electrical Engineering
- Brookhaven National Lab., Upton, NY (United States)
A new approach for processing of piecewise-constant signals is proposed. It is based on modeling the observed data as a sum of a random signal and noise. The random signal has a Gibbs distribution, and the noise is Gaussian. A MAP criterion in derived for joint estimation of the number of signal levels and reconstruction of signal. The criterion comprises of three terms, one corresponding to the likelihood of the data and two to penalties. One penalty term penalizes for unnecessary transitions, and the other, for unnecessary levels. The method has been tested on synthesized data and applied to single ion channel recording.
- Research Organization:
- Brookhaven National Lab., Upton, NY (United States)
- Sponsoring Organization:
- USDOE, Washington, DC (United States)
- DOE Contract Number:
- AC02-76CH00016
- OSTI ID:
- 224109
- Report Number(s):
- BNL--62775; CONF-9605108--1; ON: DE96008216
- Country of Publication:
- United States
- Language:
- English
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