Vertebral Augmentation with Nitinol Endoprosthesis: Clinical Experience in 40 Patients with 1-Year Follow-up

Journal Article · Sat Feb 15 04:00:00 EST 2014 · Cardiovascular and Interventional Radiology

DOI:https://doi.org/10.1007/S00270-013-0623-1· OSTI ID:22318127

Manca, Antonio ^[1]; Marcia, Stefano ^[2]; Chiara, Gabriele ^[1]; Marini, Stefano ^[2]; Baroud, Gamal ^[3]; Regge, Daniele ^[4]; Montemurro, Filippo ^[5]

---

1. Institute for Cancer Research and Treatment (IRCC), Interventional Radiology Unit (Italy)
2. Institute of Radiology, University of Cagliari (Italy)
3. University of Sherbrooke, Departement de Genie Mecanique (Canada)
4. Institute for Cancer Research and Treatment (IRCC), Radiology Unit (Italy)
5. Institute for Cancer Research and Treatment (IRCC), Internal Medicine Unit (Italy)

Purpose: This study was designed to assess the clinical outcomes of patients treated by vertebral augmentation with nitinol endoprosthesis (VNE) to treat painful vertebral compression fractures. Methods: Forty patients with one or more painful osteoporotic VCF, confirmed by MRI and accompanied by back-pain unresponsive to a minimum 2 months of conservative medical treatment, underwent VNE at 42 levels. Preoperative and postoperative pain measured with Visual Analog Scale (VAS), disability measured by Oswestry Disability Index (ODI), and vertebral height restoration (measured with 2-dimensional reconstruction CT) were compared at last follow-up (average follow-up 15 months). Cement extravasation, subsequent fractures, and implant migration were recorded. Results: Long-term follow-up was obtained in 38 of 40 patients. Both VAS and ODI significantly improved from a median of 8.0 (range 5–10) and 66 % (range 44–88 %) to 0.5 (range 0–8) and 6 % (range 6–66 %), respectively, at 1 year (p < 0.0001). Vertebral height measurements comparing time points increased in a statistically significant manner (ANOVA, p < 0.001). Overall cement extravasation rate was 9.5 %. Discal and venous leakage rates were 7.1 and 0 % respectively. No symptomatic extravasations occurred. Five of 38 (13.1 %) patients experienced new spontaneous, osteoporotic fractures. No device change or migration was observed. Conclusions: VNE is a safe and effective procedure that is able to provide long-lasting pain relief and durable vertebral height gain with a low rate of new fractures and cement leakages.

• OSTI ID: 22318127
• Journal Information: Cardiovascular and Interventional Radiology, Journal Name: Cardiovascular and Interventional Radiology Journal Issue: 1 Vol. 37; ISSN 0174-1551; ISSN CAIRDG
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
AUGMENTATION
BIOLOGICAL RECOVERY
BONE FRACTURES
CEMENTS
COMPARATIVE EVALUATIONS
COMPRESSION
DESIGN
EQUIPMENT
IMPLANTS
NICKEL ALLOYS
NMR IMAGING
PAIN
PATIENTS
TITANIUM ALLOYS
TWO-DIMENSIONAL CALCULATIONS