Biomarkers of cell senescence

Patent · Tue Feb 13 00:00:00 EST 1996

OSTI ID:201520

Dirmi, G P; Campisi, J; Peacocke, M

The present invention provides a biomarker system for the in vivo and in vitro assessment of cell senescence. In the method of the present invention, {beta}-galactosidase activity is utilized as a means by which cell senescence may be assessed either in in vitro cell cultures or in vivo. 1 fig.

• Research Organization: Univ. of California (United States)
• DOE Contract Number: AC03-76SF00098
• Assignee: Univ. of California, Oakland, CA (United States)
• Patent Number(s): US 5,491,069/A/
• Application Number: PAN: 8-198,436
• OSTI ID: 201520
• Resource Relation: Other Information: PBD: 13 Feb 1996
• Country of Publication: United States
• Language: English

Related Subjects

55 BIOLOGY AND MEDICINE
BASIC STUDIES
BIOLOGICAL MARKERS
DESIGN
GALACTOSIDASE
ENZYME ACTIVITY
ANIMAL CELLS
LIFE CYCLE