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Pharmacologic perturbation as a potential tool to increase the sensitivity of FDG-PET in the evaluation of brain tumors

Journal Article · · Journal of Nuclear Medicine
OSTI ID:198087
; ;  [1]
  1. Univ. of Texas M.D. Anderson Cancer Center, Houston, TX (United States); and others
The usefulness of F-18 FDG PET in the study of brain tumors is limited by the high baseline cortical uptake which decreases the contrast of the tumor. Two alternatives to increase the tumor/background contrast have been reported: barbiturate-induced coma and postprandial state. This project evaluates the effects of sedation with diazepam or of oral glucose intake on the brain tumor/background contrast during F-18 FDG PET studies.
OSTI ID:
198087
Report Number(s):
CONF-940605--
Journal Information:
Journal of Nuclear Medicine, Journal Name: Journal of Nuclear Medicine Journal Issue: Suppl.5 Vol. 35; ISSN JNMEAQ; ISSN 0161-5505
Country of Publication:
United States
Language:
English

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